The name "Octorara Area Schools" was officially selected at the May 4, 1953 meeting of the Board.

"Octorara" is a name that is Native American in origin and it is given to the two major streams that drain the area. Legend reports that the name refers to either "flowing waters" or to "the sun". The unique design of the proscenium arch above the high school stage is attributed to the architect's interpretation of the rising sun.

Octorara is a semi-rural community whose boundaries encompass parts of southwestern Chester County and southeastern Lancaster County. Within the school district can be found some of the richest agricultural land in the United States.